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Youngsok Choi, PhD
 Professor, Director


직위: 교수
세부전공: 생식생물학 및 발생학
연구실: 건국대학교 동물생명과학관 411호
실험실: 건국대학교 생명과학관 115호
연락처: 02-450-3969
학력 및 학위​
1988~1995  건국대학교 축산학과 농학사
1996~1998  건국대학교 축산학과 농학석사
1998~2002  미국 Texas A&M University, 농학박사
2002~2008  미국 Baylor College of Medicine, 박사후연구원
2008~2012  차의과학대학교 의생명과학과 조교수
2012~2018  차의과학대학교 의생명과학과 부교수
2018~2019  차의과학대학교 의생명과학과 교수
2016~현재    미국 Michigan State University 의대 겸임 교수
2019~현재    건국대학교 줄기세포재생공학과 교수
2012~2014  대한생식의학회 편집위원
2015~2017  한국유전학회 홍보위원
2012~현재    한국동물번식학회 편집위원회 부위원장
2015~현재    대한실험동물학회 학술위원
2017~현재    한국발생생물학회 학술위원
2017~현재    한국유전학회 기획위원
2017~현재    대한생식의학회 학술위원
2018~현재    KISTEP 생명보건의료 분야 기술수준평가 전문가
논문 / 저서
1. Hong K, Choi Y. Role of estrogen and RAS signaling in repeated implantation failure. BMB Rep. 2018 May;51(5):225-229. Review. PMID:29519295

2. Yoon H, Jang H, Kim EY, Moon S, Lee S, Cho M, Cho HJ, Ko JJ, Chang EM, Lee KA, Choi Y. Knockdown of PRKAR2B Results in the Failure of Oocyte Maturation. Cellular Physiology and Biochemistry. 2018;45:2009-2020. PMID: 29518769

3. Park HJ, Choi WS, Lee WY, Choi Y, Park C, Kim JH, Hong KH, Song H. A novel mouse model of atopic dermatitis that is T helper 2 (Th2)-polarized by an epicutaneous allergen. Environmental Toxicology and Pharmacology. 2018 Mar;58:122-130. PMID: 29329020

4. Jang H, Na Y, Hong K, Lee S, Moon S, Cho M, Park M, Lee OH, Chang EM, Lee DR, Ko JJ, Lee WS, Choi Y. Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1 promoter in primordial follicles. Journal of Pineal Research. 2017 Oct;63(3):e12432. PMID: 28658519.

5. Lee SE, Hyun H, Park MR, Choi Y, Son YJ, Park YG, Jeong SG, Shin MY, Ha HJ, Hong HS, Choi MK, Im GS, Park EW, Kim YH, Park C, Kim EY, Park SP. Production of transgenic pig as an Alzheimer's disease model using a multi- cistronic vector system. PLoS One. 2017 Jun 6;12(6):e0177933. PMID: 28586343.

6. Jang H, Hong K, Choi Y. Melatonin and fertoprotective adjuvants: Prevention against premature ovarian failure during chemotherapy. International Journal of Molecular Sciences. 2017 June 7; 18(6):1221. PMID: 28590419.

7. Kim HR, Cho KS, Kim E, Lee OH, Yoon H, Lee S, Moon S, Park M, Hong K, Na Y, Shin JE, Kwon H, Song H, Choi DH, Choi Y. Rapid expression of RASD1 is regulated by estrogen receptor-dependent intracellular signaling pathway in the mouse uterus. Molecular and Cellular Endocrinology. 2017 May 5; 446:32-39. PMID: 28188843.

8. Lee Y, Kim KH, Yoon H, Lee OH, Kim E, Park M, Jang H, Hong K, Song H, Ko JJ, Lee WS, Lee KA, Chang EM, Choi Y. RASD1 Knockdown Results in Failure of Oocyte Maturation. Cellular Physiology and Biochemistry. 2016 Dec 19; 40(6):1289-1302. PMID: 27997888.

9. Choi Y, Kim JO, Shim SH, Lee Y, Kim JH, Jeon YJ, Ko JJ, Lee WS, Kim NK. Genetic Variation of Methylenetetrahydrofolate Reductase (MTHFR) and Thymidylate Synthase (TS) Genes Is Associated with Idiopathic Recurrent Implantation Failure. PLoS One. 2016 Aug 25; 11(8):e0160884. PMID: 27560137.

10. Choi Y, Kim HR, Lim EJ, Park M, Yoon JA, Kim YS, Kim EK, Shin JE, Kim JH, Kwon H, Song H, Choi DH. Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF). PLoS One. 2016 Jun 15; 11(6):e0157696. PMID:27304912.

11. Jang HG*, Choi Y*, Kim JO, Jeon YJ, Rah H, Cho SH, Kim JH, Lee WS, Kim NK. Polymorphisms in tumor necrosis factor-alpha (-863C>A, -857C>T and +488G>A) are associated with idiopathic recurrent pregnancy loss in Korean women. Human Immunology. 2016 Jun; 77(6):506-11. PMID:27083536. (*Equal contribution)

12. Kim M, Ki BS, Hong K, Park SP, Ko JJ, Choi Y. Tudor Domain Containing Protein TDRD12 Expresses at the Acrosome of Spermatids in Mouse Testis. Asian-Australasian Journal of Animal Sciences. 2016 Jul; 29(7):944-51. PMID:26954166.

13. Bae S, Kwon H, Yoon H, Park M, Kim HR, Song H, Hong K, Choi Y. Estrogen-dependent expression of sine oculis homeobox 1 in the mouse uterus during the estrous cycle. Biochemical and Biophysical Research Communications. 2016 Apr 8; 472(3):489-95. PMID: 26940739.

14. Jang H, Lee OH, Lee Y, Yoon H, Chang EM, Park M, Lee JW, Hong K, Kim JO, Kim NK, Ko JJ, Lee DR, Yoon TK, Lee WS, Choi Y. Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary. Journal of Pineal Research. 2016 Apr;60(3):336-47. PMID: 26882203.

15. Lee KH, Lee WY, Kim DH, Lee SH, Do JT, Park C, Kim JH, Choi YS, Song H. Vitrified canine testicular cells allow the formation of spermatogonial stem cells and seminiferous tubules following their xenotransplantation into nude mice. Scientific Reports. 2016 Feb 24;6:21919. PMID: 26907750.

16. Lee KH, Lee WY, Kim JH, Park CK, Do JT, Kim JH, Choi YS, Kim NH, Song H. Subculture of Germ Cell-Derived Colonies with GATA4-Positive Feeder Cells from Neonatal Pig Testes. Stem Cells International. 2016; 2016: 6029271. PMID: 26880974.

17. Park M, Lee Y, Jang H, Lee OH, Park SW, Kim JH, Hong K, Song H, Park SP, Park YY, Ko JJ, Choi Y. SOHLH2 is essential for synaptonemal complex formation during spermatogenesis in early postnatal mouse testes. Scientific Reports. 2016 Feb 12;6:20980. PMID:26869299.

18. Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H. Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice. Scientific Reports. 2016 Feb 2;6:20242. PMID: 26833131.

19. Chang EM, Lim E, Yoon S, Jeong K, Bae S, Lee DR, Yoon TK, Choi Y*, Lee WS*. Cisplatin induces overactivation of the dormant primordial follicle through PTEN/AKT/FOXO3a pathway which leads to loss of ovarian reserve in mice. PLoS One. 2015 Dec 14;10(12):e0144245. PMID: 26656301. (*Co-corresponding author) 

20. Ko HY, Lee J, Lee YS, Choi Y, Ali BA, Al-Khedhairy AA, Kim S. Bioimaging of transcriptional activity of microRNA124a during neurogenesis. Biotechnology Letters. 2015 Nov; 37(11):2333-40. PMID: 26174608.

21. Park SY, Choi HK, Seo JS, Yoo JY, Jeong JW, Choi Y, Choi KC, Yoon HG. DNAJB1 negatively regulates MIG6 to promote epidermal growth factor receptor signaling. Biochimica et Biophysica Acta (BBA-Molecular Cell Research). 2015 Oct; 1853(10 Pt A):2722-30. PMID: 26239118.

22. Lee J, Choi K, Choi Y, Ali BA, Al-khedhairy AA, Kim S. Sperm DNA-mediated reduction of nonspecific fluorescence during cellular imaging with quantum dots. Chemical Communications (Camb). 2015 Jul 25; 51(58):11584-11586. PMID: 26096719.

23. Choi HK*, Choi Y*, Park ES*, Park SY, Lee SH, Seo J, Jeong MH, Jeong JW, Jeong JH, Lee PC, Choi KC, Yoon HG. Programmed cell death 5 mediates HDAC3 decay to promote genotoxic stress response. Nature Communications. 2015 Jun 16; 6:7390. PMID: 26077467. (?Equal contribution by these authors)

24. Park SY, Choi HK, Jo SH, Seo J, Han EJ, Choi KC, Jeong JW, Choi Y*, Yoon HG*. YAF2 promotes TP53-mediated genotoxic stress response via stabilization of PDCD5. Biochimica et Biophysica Acta (BBA-Molecular Cell Research). 2015 May;1853 (5):1060-1072. PMID: 25603536. (*Co-corresponding author )

25. Hong K, Kim YJ, Choi Y. Function of TET proteins in germ cell reprogramming. Genes & Genomics. 2015 Mar;37(3):223-229. PMID: 

26. Hong KS, Bae D, Choi Y, Kang SW, Moon SH, Lee HT, Chung HM. A porous membrane-mediated isolation of mesenchymal stem cells from human embryonic stem cells. Tissue Engineering Part C: Methods. 2015 Mar;21(3):322-329. PMID: 25190318.

27. Park SY, Choi HK, Choi Y, Kwak S, Choi KC, Yoon HG. Deubiquitinase OTUD5 mediates the sequential activation of PDCD5 and p53 in response to genotoxic stress. Cancer Letters. 2015 Feb 1;357(1):419-427. PMID: 25499082.

28. Lee OH, Lee J, Lee KH, Woo YM, Kang JH, Yoon HG, Bae SK, Songyang Z, Oh SH, Choi Y. Role of the focal adhesion protein TRIM15 in colon cancer development. Biochimica et Biophysica Acta (BBA-Molecular Cell Research). 2015 Feb;1853(2):409-421. PMID: 25450970.

29. Choi HK*, Choi Y*, Kang H, Lim EJ, Park SY, Lee HS, Park JM, Moon J, Kim YJ, Choi I, Joe EH, Choi KC, Yoon HG. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Human Molecular Genetics. 2015 Feb 15;24(4):1127-1141. PMID: 25305081. (?Equal contribution)

30. Lim W, Bae SM, Jo G, Bazer FW, Choi Y*, Song G*. Prostaglandin D₂ synthase related to estrogen in the female reproductive tract. Biochemical and Biophysical Research Communications. 2015 Jan 2;456(1):355-360. PMID: 25475724. (*Co-coresponding author )

31. Jeong JH, Park M, Park M, Lim EJ, Kim HR, Song H, Park SG, Choi EJ, Hong KH, Lee DR, Ko JJ, Choi Y. The expression of aminoacyl-tRNA-synthetase-interacting multifunctional protein-1 (Aimp1) is regulated by estrogen in the mouse uterus. Molecular and Cellular Endocrinology. 2015 Jan 5;399:78-86. PMID: 25132647.

32. Bae H, Lim W, Bae SM, Bazer FW, Choi Y*, Song G*. Avian prostatic acid phosphatase: estrogen regulation in the oviduct and epithelial cell-derived ovarian carcinomas. Biology of Reproduction. 2014 Jul;91(1):3, 1-8. PMID: 24829029. (*Co-coresponding author )

33. Joo JY, Lee J, Ko HY, Lee YS, Lim DH, Kim EY, Cho S, Hong KS, Ko JJ, Lee S, Lee YS, Choi Y, Lee KA, Kim S. Microinjection free delivery of miRNA inhibitor into zygotes. Scientific Report. 2014 Jun 24;4:5417. PMID:24957209.

34. Hong KS, Byun KH, Seo J, Lee HJ, Choi JJ, Kim KS, Choi Y, Moon SH, Chung HM. Modification to the injection needle to a screw needle improves effective cell delivery in acute myocardial infarction. Biotechnology Letters. 2014 Apr;36(4):859-868. PMID: 24322769.

35. Rah H, Jeon YJ, Ko JJ, Kim JH, Kim YR, Cha SH, Choi Y, Lee WS, Kim NK. Association of inhibin α gene promoter polymorphisms with risk of idiopathic primary ovarian insufficiency in Korean women. Maturitas. 2014 Feb;77(2):163-167. PMID: 24269065.

36. Habib O, Habib G, Moon SH, Hong KS, Do JT, Choi Y, Chang SW, Chung HM. Ground-state conditions promote robust Prdm14 reactivation and maintain an active Dlk1-Dio3 region during reprogramming. Molecular Cells. 2014 Jan;37(1):31-35. PMID: 24552707.

37. Lee OH, Kim J, Kim JM, Lee H, Kim EH, Bae SK, Choi Y, Nam HS, Heo JH. Decreased expression of sirtuin 6 is associated with release of high mobility group box-1 after cerebral ischemia. Biochemical and Biophysical Research Communications. 2013 Aug 23;438(2):388-394. PMID:23899523.

38. Kim M, Park HJ, Seol JW, Jang JY, Cho YS, Kim KR, Choi Y, Lydon JP, Demayo FJ, Shibuya M, Ferrara N, Sung HK, Nagy A, Alitalo K, Koh GY. VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. EMBO Molecular Medicine. 2013 Sep;5(9):1415-1430. PMID: 23853117.

39. Lim EJ, Choi Y. Transcription factors in the maintenance and survival of primordial follicles. Clin Exp Reprod Med. 2012 Dec;39(4):127-131. PMID: 23346521.

40. Rah H, Jeon YJ, Choi Y, Shim SH, Yoon TK, Choi DH, Cha SH, Kim NK. Association of methylenetetrahydrofolate reductase (MTHFR 677C>T) and thymidylate synthase (TSER and TS 1494del6) polymorphisms with premature ovarian failure in Korean women. Menopause. 2012 Nov;19(11):1260-1266. PMID: 22713864.

41. Rah H, Jeon YJ, Choi Y, Shim SH, Ko JJ, Yoon TK, Cha SH, Kim NK. Association between kinase insert domain-containing receptor polymorphisms (-604T>C, 1192G>A, 1719A>T) and premature ovarian failure in Korean women. Menopause. 2012 Sep;19(9):1037-1042. PMID: 22510937.

42. Seo H, Choi Y, Shim J, Choi Y, Ka H. Regulatory mechanism for expression of IL1B receptors in the uterine endometrium and effects of IL1B on prostaglandin synthetic enzymes during the implantation period in pigs. Biology of Reproduction. 2012 Aug 9;87(2):31. PMID:22572995.

43. Rah H, Choi YS, Jeon YJ, Choi Y, Cha SH, Choi DH, Ko JJ, Shim SH, Kim NK. Solute Carrier Family 19, member 1 (SLC19A1) polymorphisms (-43T>C, 80G>A, and 696C>T), and haplotypes in idiopathic recurrent spontaneous abortion in a Korean population. Reproductive Sciences. 2012 May;19(5):513-519. PMID: 22344739.

44. Bak CW, Yoon TK, Choi Y. Functions of PIWI proteins in spermatogenesis. Clin Exp Reprod Med. 2011 Jun;38(2):61-67. PMID: 22384420. 

45. Jeon YJ, Choi Y, Shim SH, Choi YS, Ko JJ, Yoon TK, Cha SH, Kim NK. Vascular endothelial growth factor gene polymorphisms in Korean patients with premature ovarian failure. Eur J Obstet Gynecol Reprod Biol. 2011 Nov;159(1):138-142. PMID: 21831507.

46. Choi HW, Kim JS, Choi S, Jang HJ, Kim MJ, Choi Y, Scholer HR, Chung HM, Do JT. Neural stem cells achieve and maintain pluripotency without feeder cells. PLoS One. 2011;6(6):e21367. PMID: 21738644.

47. Choi YS, Kwon H, Kim JH, Shin JE, Choi Y, Yoon TK, Choi DH, Kim NK. Haplotype-based association of ACE I/D, AT1R 1166A>C, and AGT M235T polymorphisms in renin-angiotensin-aldosterone system genes in Korean women with idiopathic recurrent spontaneous abortions. Eur J Obstet Gynecol Reprod Biol. 2011 Oct;158(2):225-228. PMID: 21636204.

48. Lechowska A, Bilinski S, Choi Y, Shin Y, Kloc M, Rajkovic A. Premature ovarian failure in nobox-deficient mice is caused by defects in somatic cell invasion and germ cell cyst breakdown. J Assist Reprod Genet. 2011 Jul;28(7):583-589. PMID: 21369782.

49. Shin YH, Choi Y, Erdin SU, Yatsenko SA, Kloc M, Yang F, Wang PJ, Meistrich ML, Rajkovic A. Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genetics. 2010 Nov 4;6(11):e1001190. PMID: 21079677.

50. Do JT, Choi HW, Choi Y, Scholer HR. Pluripotent hybrid cells contribute to extraembryonic as well as embryonic tissues. Stem Cells and Development. 2011 Jun;20(6):1063-1069. PMID:20946016.

51. Choi M, Lee OH, Jeon S, Park M, Lee DR, Ko JJ, Yoon TK, Rajkovic A, Choi Y. The oocyte-specific transcription factor, Nobox, regulates the expression of Pad6, a peptidylarginine deiminase in the oocyte. FEBS Letters. 2010 Aug 20;584(16):3629-3634. PMID: 20659469.

52. Choi Y, Jeon S, Choi M, Lee MH, Park M, Lee DR, Jun KY, Kwon Y, Lee OH, Song SH, Kim JY, Lee KA, Yoon TK, Rajkovic A, Shim SH. Mutations in SOHLH1 gene associate with nonobstructive azoospermia. Human Mutation. 2010 Jul;31(7):788-793. PMID: 20506135.

53. Kang HB*, Choi Y*, Lee JM, Choi KC, Kim HC, Yoo JY, Lee YH, Yoon HG. The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription. FEBS Letters. 2009 Jun 18;583(12):1880-1886. PMID: 19481544. (?Equal contribution by these authors)

54. Fleming JA, Song G, Choi Y, Spencer TE, Bazer FW. Interferon regulatory factor 6 (IRF6) is expressed in the ovine uterus and functions as a transcriptional activator. Molecular and Cellular Endocrinology. 2009 Feb 27;299(2):252-260. PMID: 19022341.

55. Choi Y, Yuan D, Rajkovic A. Germ cell-specific transcriptional regulator sohlh2 is essential for early mouse folliculogenesis and oocyte-specific gene expression. Biology of Reproduction. 2008 Dec;79(6):1176-1182. PMID: 18753606.

56. Krotz SP, Ballow DJ, Choi Y, Rajkovic A. Expression and localization of the novel and highly conserved gametocyte-specific factor 1 during oogenesis and spermatogenesis. Fertility & Sterility. 2009 May;91(5 Suppl):2020-2024. PMID: 18706558.

57. Choi Y, Ballow DJ, Xin Y, Rajkovic A. Lim homeobox gene, lhx8, is essential for mouse oocyte differentiation and survival. Biology of Reproduction. 2008 Sep;79(3):442-449. PMID: 18509161.

58. Zhao H, Chen ZJ, Qin Y, Shi Y, Wang S, Choi Y, Simpson JL, Rajkovic A. Transcription factor FIGLA is mutated in patients with premature ovarian failure. Am J Hum Genet. 2008 Jun;82(6):1342-1348. PMID: 18499083.

59. Qin Y, Choi Y, Zhao H, Simpson JL, Chen ZJ, Rajkovic A. NOBOX homeobox mutation causes premature ovarian failure. Am J Hum Genet. 2007 Sep;81(3):576-581. PMID: 17701902.

60. Choi Y, Qin Y, Berger MF, Ballow DJ, Bulyk ML, Rajkovic A. Microarray analyses of newborn mouse ovaries lacking Nobox. Biology of Reproduction. 2007 Aug;77(2):312-319. PMID: 17494914.

61. Choi Y, Rajkovic A. Characterization of NOBOX DNA binding specificity and its regulation of Gdf9 and Pou5f1 promoters. J Biol Chem. 2006 Nov 24;281(47):35747-35756. PMID: 16997917.

62. Ballow DJ, Xin Y, Choi Y, Pangas SA, Rajkovic A. Sohlh2 is a germ cell-specific bHLH transcription factor. Gene Expression Patterns. 2006 Oct;6(8):1014-1018. PMID: 16765102.

63. Pangas SA, Choi Y, Ballow DJ, Zhao Y, Westphal H, Matzuk MM, Rajkovic A. Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8090-8095. PMID: 16690745.

64. Gray CA, Abbey CA, Beremand PD, Choi Y, Farmer JL, Adelson DL, Thomas TL, Bazer FW, Spencer TE. Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus. Biology of Reproduction. 2006 Feb;74(2):383-394. PMID: 16251498.

65. Yoon HG, Choi Y, Cole PA, Wong J. Reading and function of a histone code involved in targeting corepressor complexes for repression. Molecular and Cellular Biology. 2005 Jan;25(1):324-335. PMID: 15601853.

66. Kim S, Choi Y, Bazer FW, Spencer TE. Identification of genes in the ovine endometrium regulated by interferon tau independent of signal transducer and activator of transcription 1. Endocrinology. 2003 Dec;144(12):5203-5214. PMID: 12960022.

67. Kim S, Choi Y, Spencer TE, Bazer FW. Effects of the estrous cycle, pregnancy and interferon tau on expression of cyclooxygenase two (COX-2) in ovine endometrium. Reproductive and Biological Endocrinology. 2003 Aug 20;1:58. PMID: 12956885.

68. Choi Y, Johnson GA, Spencer TE, Bazer FW. Pregnancy and interferon tau regulate major histocompatibility complex class I and beta2-microglobulin expression in the ovine uterus. Biology of Reproduction. 2003 May;68(5):1703-1710. PMID: 12606392.

69. Stewart MD, Choi Y, Johnson GA, Yu-Lee LY, Bazer FW, Spencer TE. Roles of Stat1, Stat2, and interferon regulatory factor-9 (IRF-9) in interferon tau regulation of IRF-1. Biology of Reproduction. 2002 Feb;66(2):393-400. PMID: 11804954.

70. Choi Y, Johnson GA, Burghardt RC, Berghman LR, Joyce MM, Taylor KM, Stewart MD, Bazer FW, Spencer TE. Interferon regulatory factor-two restricts expression of interferon-stimulated genes to the endometrial stroma and glandular epithelium of the ovine uterus. Biology of Reproduction. 2001 Oct;65(4):1038-1049. PMID: 1166724.

71. Fleming JAW*, Choi Y*, Johnson GA, Spencer TE, Bazer FW. Cloning of the ovine estrogen receptor-alpha promoter and functional regulation by ovine interferon-tau. Endocrinology. 2001 Jul;142(7):2879-2887. PMID: 11416007. (?Equal contribution by these authors)

72. Johnson GA, Stewart MD, Gray CA, Choi Y, Burghardt RC, Yu-Lee LY, Bazer FW, Spencer TE. Effects of the estrous cycle, pregnancy, and interferon tau on 2',5'-oligoadenylate synthetase expression in the ovine uterus. Biology of Reproduction. 2001 May;64(5):1392-1399. PMID: 11319143

Iqbal MA, Hong K, Kim JH, Choi Y. Severe combined immunodeficiency pig as an emerging animal model for human diseases and regenerative medicines. BMB Rep. 2019 Nov;52(11):625-634. doi: 10.5483/BMBRep.2019.52.11.267. Erratum in: BMB Rep. 2019 Dec;52(12):718-727. PMID: 31722780; PMCID: PMC6889892.

78. Moon S, Lee OH, Lee S, Lee J, Park H, Park M, Chang EM, Park KH, Choi Y. STK3/4 Expression Is Regulated in Uterine Endometrial Cells during the Estrous Cycle. Cells. 2019 Dec 15;8(12):1643. doi: 10.3390/cells8121643. PMID: 31847471; PMCID: PMC6952811.

79. Iqbal MA, Hong K, Kim JH, Choi Y. Erratum to: Severe combined immunodeficiency pig as an emerging animal model for human diseases and regenerative medicines. BMB Rep. 2019 Dec;52(12):718-727. Erratum for: BMB Rep. 2019 Nov;52(11):625-634. PMID: 31878988.

80. Yoo H, Lee YJ, Park C, Son D, Choi DY, Park JH, Choi HJ, La HW, Choi YJ, Moon EH, Saur D, Chung HM, Song H, Do JT, Jang H, Lee DR, Park C, Lee OH, Cho SG, Hong SH, Kong G, Kim JH, Choi Y, Hong K. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. Cell Death Dis. 2020 Jan 6;11(1):14. doi: 10.1038/s41419-019-2201-1. PMID: 31908356; PMCID: PMC6944698.

81. Gurunathan S, Jeyaraj M, La H, Yoo H, Choi Y, Do JT, Park C, Kim JH, Hong K. Anisotropic Platinum Nanoparticle-Induced Cytotoxicity, Apoptosis, Inflammatory Response, and Transcriptomic and Molecular Pathways in Human Acute Monocytic Leukemia Cells. Int J Mol Sci. 2020 Jan 9;21(2):440. doi: 10.3390/ijms21020440. PMID: 31936679; PMCID: PMC7014054.

82. Cho M, Lee OH, Chang EM, Lee S, Moon S, Lee J, Park H, Park KH, Park C, Hong K, Choi Y. BIRC5 Expression is Regulated in Uterine Epithelium During the Estrous Cycle. Genes (Basel). 2020 Mar 6;11(3):282. doi: 10.3390/genes11030282. PMID: 32155884; PMCID: PMC7140846.

83. Chei S, Oh HJ, Jang H, Lee K, Jin H, Choi Y, Lee BY. Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and NLRP3 Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. Foods. 2020 Apr 22;9(4):526. doi: 10.3390/foods9040526. PMID: 32331214; PMCID: PMC7231237.

84. Jeong CH, Kwon HC, Cheng WN, Kim DH, Choi Y, Han SG. Aluminum exposure promotes the metastatic proclivity of human colorectal cancer cells through matrix metalloproteinases and the TGF-β/Smad signaling pathway. Food Chem Toxicol. 2020 Jul;141:111402. doi: 10.1016/j.fct.2020.111402. Epub 2020 May 8. PMID: 32437896.

85. Han MJ, Lee WJ, Choi J, Hong YJ, Uhm SJ, Choi Y, Do JT. Inhibition of neural stem cell aging through the transient induction of reprogramming factors. J Comp Neurol. 2021 Feb;529(3):595-604. doi: 10.1002/cne.24967. Epub 2020 Jun 28. PMID: 32510600.

86. Seo BJ, Choi J, La H, Habib O, Choi Y, Hong K, Do JT. Role of mitochondrial fission-related genes in mitochondrial morphology and energy metabolism in mouse embryonic stem cells. Redox Biol. 2020 Sep;36:101599. doi: 10.1016/j.redox.2020.101599. Epub 2020 May 30. PMID: 32521505; PMCID: PMC7286981.

87. Gurunathan S, Qasim M, Choi Y, Do JT, Park C, Hong K, Kim JH, Song H. Antiviral Potential of Nanoparticles-Can Nanoparticles Fight Against Coronaviruses? Nanomaterials (Basel). 2020 Aug 21;10(9):1645. doi: 10.3390/nano10091645. PMID: 32825737; PMCID: PMC7557932.

88. Ryu MJ, Seo BJ, Choi YJ, Han MJ, Choi Y, Chung MK, Do JT. Mitochondrial and Metabolic Dynamics of Endometrial Stromal Cells During the Endometrial Cycle. Stem Cells Dev. 2020 Sep 24. doi: 10.1089/scd.2020.0130. Epub ahead of print. PMID: 32867608.

89. Yoo H, Choi D, Choi Y. Conjugation of vascular endothelial growth factor to poly lactic-co-glycolic acid nanospheres enhances differentiation of embryonic stem cells to lymphatic endothelial cells. Anim Biosci. 2021 Apr;34(4):533-538. doi: 10.5713/ajas.20.0202. Epub 2020 Aug 21. PMID: 32882780; PMCID: PMC7961292.

90. Shin J, Bae J, Park S, Kang HG, Shin SM, Won G, Kim JS, Cho SG, Choi Y, Oh SM, Shin J, Kim JS, Park HW. mTOR-Dependent Role of Sestrin2 in Regulating Tumor Progression of Human Endometrial Cancer. Cancers (Basel). 2020 Sep 4;12(9):2515. doi: 10.3390/cancers12092515. PMID: 32899752; PMCID: PMC7565818.

91. Lee OH, Woo YM, Moon S, Lee J, Park H, Jang H, Park YY, Bae SK, Park KH, Heo JH, Choi Y. Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression. Aging (Albany NY). 2020 Nov 10;12(21):20946-20967. doi: 10.18632/aging.202176. Epub 2020 Nov 10. PMID: 33171439; PMCID: PMC7695388.

92. Lee WJ, Lee JE, Hong YJ, Yoon SH, Song H, Park C, Hong K, Choi Y, Do JT. Generation of brain organoids from mouse ESCs via teratoma formation. Stem Cell Res. 2020 Dec;49:102100. doi: 10.1016/j.scr.2020.102100. Epub 2020 Nov 24. PMID: 33260068.

93. Kim YS, Yang SC, Park M, Choi Y, DeMayo FJ, Lydon JP, Kim HR, Lim HJ, Song H. Different Cre systems induce differential microRNA landscapes and abnormalities in the female reproductive tracts of Dgcr8 conditional knockout mice. Cell Prolif. 2021 Mar;54(3):e12996. doi: 10.1111/cpr.12996. Epub 2021 Jan 26. PMID: 33496365; PMCID: PMC7941225.

94. Kim HJ, Lee S, Lee JH, Park JM, Hong SJ, Lee OH, Park JS, Choi Y, Park KH. TRITC-Loaded PLGA Nanoparticles as Drug Delivery Carriers in Mouse Oocytes and Embryos. ACS Appl Mater Interfaces. 2021 Feb 10;13(5):5975-5988. doi: 10.1021/acsami.0c19792. Epub 2021 Jan 27. PMID: 33502166.

95. Lee J, Park H, Moon S, Do JT, Hong K, Choi Y. Expression and Regulation of CD73 during the Estrous Cycle in Mouse Uterus. Int J Mol Sci. 2021 Aug 30;22(17):9403. doi: 10.3390/ijms22179403. PMID: 34502315; PMCID: PMC8431015.

96. Lee Y, Cho HS, Choi M, Prathap S, Soundrarajan N, Choi Y, Song H, Hong K, Park C. Comparison of DNA/RNA yield and integrity between PMAP36-mediated and other bacterial lysis methods. J Microbiol Methods. 2022 Feb;193:106396. doi: 10.1016/j.mimet.2021.106396. Epub 2021 Dec 16. PMID: 34921868.

97. Lee OH, Lee S, Park M, Moon S, Hwang S, Kim B, Kim CY, Lee DR, Shim SH, Park KH, Chung HM, Choi Y. Generation of a B2M homozygous knockout human somatic cell nuclear transfer-derived embryonic stem cell line using the CRISPR/Cas9 system. Stem Cell Res. 2021 Dec 27;59:102643. doi: 10.1016/j.scr.2021.102643. Epub ahead of print. PMID: 34971932.

98. Moon S, Hwang S, Kim B, Lee S, Kim H, Lee G, Hong K, Song H, Choi Y. Hippo Signaling in the Endometrium. Int J Mol Sci. 2022 Mar 31;23(7):3852. doi: 10.3390/ijms23073852. PMID: 35409214; PMCID: PMC8998929.

99. La H, Yoo H, Park YB, Thang NX, Park C, Yoo S, Lee H, Choi Y, Song H, Do JT, Hong K. Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development. Cells. 2022 May 19;11(10):1692. doi: 10.3390/cells11101692. PMID: 35626729; PMCID: PMC9139870.

100. Kim B, Choi Y. The Development, Differentiation, and Toxicity in Reproduction. Int J Mol Sci. 2022 Jun 28;23(13):7183. doi: 10.3390/ijms23137183. PMID: 35806199; PMCID: PMC9266829.

101. Ki BS, Shim SH, Park C, Yoo H, La H, Lee OH, Kwon Y, Skalnik DG, Okada Y, Yoon HG, Kim JH, Hong K, Choi Y. Epigenetic regulator Cfp1 safeguards male meiotic progression by regulating meiotic gene expression. Exp Mol Med. 2022 Aug;54(8):1098-1108. doi: 10.1038/s12276-022-00813-0. Epub 2022 Aug 2. PMID: 35918532; PMCID: PMC9440128.

102. Moon S, Lee OH, Kim B, Park J, Hwang S, Lee S, Lee G, Kim H, Song H, Hong K, Cho J, Choi Y. Estrogen Regulates the Expression and Localization of YAP in the Uterus of Mice. Int J Mol Sci. 2022 Aug 29;23(17):9772. doi: 10.3390/ijms23179772. PMID: 36077170; PMCID: PMC9456404.

103. Kim B, Park KH, Lee OH, Lee G, Kim H, Lee S, Hwang S, Kim YB, Choi Y. Effect of severe acute respiratory syndrome coronavirus 2 infection during pregnancy in K18-hACE2 transgenic mice. Anim Biosci. 2023 Jan;36(1):43-52. doi: 10.5713/ab.22.0143. Epub 2022 Sep 2. PMID: 36108690; PMCID: PMC9834656.

104. Lee H, You SY, Han DW, La H, Park C, Yoo S, Kang K, Kang MH, Choi Y, Hong K. Dynamic Change of R-Loop Implicates in the Regulation of Zygotic Genome Activation in Mouse. Int J Mol Sci. 2022 Nov 18;23(22):14345. doi: 10.3390/ijms232214345. PMID: 36430821; PMCID: PMC9699122.

105. Yoo S, Lee EJ, Thang NX, La H, Lee H, Park C, Han DW, Uhm SJ, Song H, Do JT, Choi Y, Hong K. INO80 Is Required for the Cell Cycle Control, Survival, and Differentiation of Mouse ESCs by Transcriptional Regulation. Int J Mol Sci. 2022 Dec 6;23(23):15402. doi: 10.3390/ijms232315402. PMID: 36499727; PMCID: PMC9740483.

106. Lee R, Park HJ, Lee WY, Choi Y, Song H. Nanoscale level gelatin-based scaffolds enhance colony formation of porcine testicular germ cells. Theriogenology. 2023 May ;202:125-135.doi: 10.1016/j.theriogenology. 2023.03.013. Epub 2023 Mar 14. PMID: 36958136.
수상 / 공훈
1995   건국대학교 총장상
2001   CERH Fellowship, Texas A&M University
2001   Final list on the Trainee Research Competition at the 34th Annual Meeting of the                        Society for the Study of Reproduction (SSR)
2001   United States Department of Agriculture National Research Initiative (USDA-NRI)                       Travel Fellowship at the 34th Annual Meeting of the Society for the Study of                                 Reproduction (SSR)
2001   Federation of American Societies for Experimental Biology (FASEB- MARC) program                 Travel Award at the 34th Annual Meeting of the Society for the Study of Reproduction               (SSR)
2002   United States Department of Agriculture National Research Initiative (USDA-NRI)                        Travel Fellowship at the 35th Annual Meeting of the Society for the Study of                                Reproduction (SSR)
2005   Burroughs Wellcome Fund Travel Fellowship at the 38th Annual Meeting of the Society              for the Study of Reproduction (SSR)
2006   Lalor Foundation Travel Fellowship at the 39th Annual Meeting of the Society for the                  Study of Reproduction (SSR)
2006   Honorable Mention for outstanding poster presentation at the Texas Forum on                            Reproductive Sciences (TFRS)
2006   Bioneer Award at the Korean-American Bio-Medical Scientists Symposiums
2007   Best platform presentation at the Texas Forum on Reproductive Sciences (TFRS)
2007   Bioneer Award (Best poster presentation) at the Korean-American Bio-Medical                         Scientists Symposiums
2009   Poster award for outstanding poster presentation at 7th Conference of the Pacific Rim             Society for Fertility and Sterility (PRSFS) and Annual meeting of Taiwanese Society for              Reproductive Medicine (TSRM)
2011   Outstanding Topic Presentation Award at 15th CHA-BIO Conference 
2014   First scientific program prize poster at 70th American Society for Reproductive                         Medicine Symposium (ASRM)
2015   Best poster presentation award at 10th Pacific-Rim Society for Reproductive Medicine             Symposium (PSRM)
2016   First scientific program prize poster at 72nd American Society for Reproductive                         Medicine Symposium (ASRM)
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